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Dermatology Xagena

The results from the one-year phase 3 CHRONOS study have shown that patients receiving the investigational drug Dupilumab ( Dupixent ) with topical corticosteroids ( TCS ) achieved significantly impro ...


Alopecia areata is an autoimmune disease characterized by hair loss mediated by CD8+ T cells. There are no reliably effective therapies for alopecia areat . Based on recent developments in the underst ...


Women represent nearly 8 out of every 10 people with autoimmune diseases. Although the hugely disproportionate statistics are well known, the scientific community is still trying to figure out why wom ...


Findings of a phase 3 study of patients with moderate to severe psoriasis demonstrating that nearly half of adult patients treated with Adalimumab ( Humira ) has achieved at least a 75% improvement in ...


The New England Journal of Medicine ( NEJM ) has published detailed results from three pivotal phase 3 studies, UNCOVER-1, UNCOVER-2 and UNCOVER-3, that have demonstrated the efficacy and safety of Ix ...


Concern regarding adverse effects of Finasteride ( Propecia ) is increasing. The aim of a study was to determine the type and frequency of symptoms in men having long-term sexual and non-sexual side e ...


The increased rates of cardiovascular morbidity and mortality in patients with psoriasis are not adequately explained by traditional risk factors. Whether concomitant sleep disorders modify the risk o ...


Keytruda ( Pembrolizumab ) is a humanized monoclonal antibody that works by increasing the ability of the body’s immune system to help detect and fight tumor cells. Pembrolizumab blocks the interactio ...


Few therapeutic alternatives currently exist in the treatment of papulopustular rosacea. The aim of a study was to demonstrate superiority of once-daily Ivermectin ( Efacti; Soolantra ) 1% cream on ...


Chemotherapy-induced alopecia ( CIA ) is a highly distressing event for cancer patients. A study aimed to assess the efficacy of various interventions in the prevention of chemotherapy-induced alopeci ...


Side effects associated with oral Finasteride ( 1 mg/d ) and topical 5% Minoxidil have been previously described. The long-term adverse effects and causes of long-term therapy withdrawal in patien ...


There is strong evidence for an autoimmune etiology of alopecia areata. Interleukin-17A ( IL-17A ) is a Th17 proinflammatory cytokine that has been linked to the pathogeneses of diverse autoimmune and ...


New data demonstrating that Cosentyx ( Secukinumab ) provides high levels of skin clearance and sustained efficacy in patients with moderate-to-severe plaque psoriasis while maintaining a favorable sa ...


The results of a phase I study in advanced melanoma suggested complementary clinical activity with Nivolumab ( Opdivo ), a PD-1 checkpoint inhibitor, plus Ipilimumab ( Yervoy ), a CTLA-4 checkpoint in ...


Keytruda ( Pembrolizumab ) is indicated in the United States at a dose of 2 mg/kg administered as an intravenous infusion over 30 minutes every three weeks for the treatment of patients with ...